Current Treatments
BETASERON® (interferon beta-1b) is indicated for the treatment of relapsing forms of multiple sclerosis to reduce the frequency of clinical exacerbations. Patients with multiple sclerosis in whom efficacy has been demonstrated include patients who have experienced a first clinical episode and have MRI features consistent with multiple sclerosis

AVONEX® (Interferon beta-1a) is a 166 amino acid glycoprotein with a predicted molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into which the human interferon beta gene has been introduced. The amino acid sequence of AVONEX® is identical to that of natural human interferon beta.

COPAXONE is the brand name for glatiramer acetate (formerly known as copolymer-1). Glatiramer acetate, the active ingredient of COPAXONE, consists of the acetate salts of synthetic polypeptides, containing four naturally occurring amino acids: L-glutamic acid, L-alanine, L-tyrosine, and L-lysine with an average molar fraction of 0.141, 0.427, 0.095, and 0.338, respectively. The average molecular weight of glatiramer acetate is 5,000 – 9,000 daltons. Glatiramer acetate is identified by specific antibodies.

Rebif® (interferon beta-1a) is a purified 166 amino acid glycoprotein with a molecular weight of approximately 22,500 daltons. It is produced by recombinant DNA technology using genetically engineered Chinese Hamster Ovary cells into which the human interferon beta gene has been introduced. The amino acid sequence of Rebif® is identical to that of natural fibroblast derived human interferon beta. Natural interferon beta and interferon beta-1a (Rebif®) are glycosylated with each containing a single N-linked complex carbohydrate moiety.

Tysabri is a monoclonal antibody that affects the actions of the body's immune system. Monoclonal antibodies are made to target and destroy only certain cells in the body. This may help to protect healthy cells from damage. Tysabri is used to treat relapsing forms of multiple sclerosis. 		Gilenya™ is a new class of medication called a phingosine 1-phosphate receptormodulator, which is thought to act by retaining certain white blood cells (lympohcytes) in the lymph nodes, thereby preventing those cells from crossing the blood-brain barrier into the central nervous system (CNS). Preventing the entry of these cells into the CNS reduces inflammatory damage to nerve cells.

Early Symptoms
The most common early symptoms of MS include:
* Tingling * Numbness
* Loss of balance
* Weakness in one or more limbs
* Blurred or double vision

Less common symptoms of MS may include
* Slurred speech
* Sudden onset of paralysis
* Lack of coordination
* Cognitive difficulties
Listed above, the early symptoms. I tend to be a poster child for these. The symptoms that occur later on are too numerous just to list. There will be a link included that will get you to a site where these symptoms are listed and explained. Keep in mind that someone may have some of these or many of these, there is no way to tell.
Multiple sclerosis statistics show that approximately 250,000 to 350,000 people in the United States have been diagnosed with this disease. The life expectancy for people with multiple sclerosis is nearly the same as for those without MS. Because of this, multiple sclerosis statistics place the annual cost of MS in the United States in the billions of dollars. MS is five times more prevalent in temperate climates -- such as those found in the northern United States, Canada, and Europe -- than in tropical regions. Furthermore, the age of 15 seems to be significant in terms of risk for developing the disease. Some studies indicate that a person moving from a high-risk (temperate) to a low-risk (tropical) area before the age of 15 tends to adopt the risk (in this case, low) of the new area and vice versa. Other studies suggest that people moving after age 15 maintain the risk of the area where they grew up.

Thursday, March 14, 2013

MS & You: What's Happening near YOU

Register now! Because MS affects more than just the individual diagnosed, all our programs welcome friends and family members unaccompanied by a person with MS. Outside organization events Young Adults with MS – Wakefield MA: Meet Caitlin Dion, MS Nurse from Lahey MS Clinic, on Thursday March 14 for “Ask the Nurse”. Beebe Library 345 Main St. Contact Adam at 781-548-9202 or adam.pinkney@ymail.com MS Awareness Week – What will you do to Join the Movement! You & Your Family Game On! Multicultural Outreach: Dorchester MA Kids Get MS Too: for families of children diagnosed with MS Caring Connections: for family & friends who have a loved one with MS Are you diagnosed in the past 5 years? Beyond Diagnosis: Moving Forward – multiple sites Can We Talk?: Teleconference series Education and Health: Employment Teleconferences and Spring Teleconference Series: Missed a call? You can listen to recordings MS Care Fair: Attleboro MA (registration coming soon) NH Spring Education Day: Concord NH VT Spring Education Day: Stowe VT MS: Living Now & Looking Forward: Randolph MA (registration coming soon) Vacation Week: for people requiring a high level of accessibility Programs without Borders Computer Outreach Program Stay connected! For people who are restricted to their homes or living in long term care facilities without access to a computer. Contact Allyssa at 800-34-4867, option 2, ext 87402 Emotional Support in-person, on the phone, caregiver, professionally led and peer led. Get fit & have fun! Physical Wellness Reimbursement and Adaptive Recreation Reimbursement Action Alert: Be a part of the issues important to people with MS at the federal, state and local levels. Online Resources: Teleconferences, Ask the Expert, Knowledge is Power, Learn Online & more Making Connections: Share what you know when, where and how you want. Access to the best resources the MS community can bring you. Volunteer! Work in, around and behind the scenes. To learn more email Brenda.Barbour@nmss.org WALK, BIKE, RUN, CLIMB, PULL, BOAT, Muckfest, Challenge and DIY Fundraising SSDI Questions? Interested in checking in with our expert? Please call 781-693-5155 to schedule a phone consultation. Information & Referral Resource Center: Resources & services; financial assistance; Dora Lipcon Lending Library; care management & more. Contact: generalmailboxgne@nmss.org or 1-800-344-4867 To find out about other programs & events or to register: Online www.MSnewengland.org Call 1-800-344-4867 Be a fan of the Greater New England Chapter! www.facebook.com/MSnewengland
Posted by Steve at Thursday, March 14, 2013

No comments:

Post a Comment

Subscribe to: Post Comments (Atom)

About Me

My photo
North Grafton, Massachusetts, United States
Well-educated, disabled at this point with Multiple Sclerosis. I am very glad that I was able to do the things that I have been able to do over the years. had to change the picture, this one's more realistic.